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What is Vitrification (Oocyte/Embryo)?
Vitrification is an advanced, ultra-rapid freezing technique used to preserve oocytes (eggs) and embryos by turning them into a glass-like solid, without the formation of ice crystals. This method ensures the highest survival rates upon warming (unfreezing) compared to traditional slow-freezing methods. Vitrification helps in planning for pregnancy according to one’s needs and requirements.
Who can opt for Vitrification (Oocyte/Embryo)?
Vitrification is ideal for:
- Couples undergoing IVF, for whom fresh embryo transfer is not feasible – because of thin endometrium, fluid in cavity, medical reasons (or) risk of OHSS
- Women/couples wishing to delay parenthood for personal, career, or health-related reasons
- Couples undergoing IVF having surplus embryos can preserve embryos for future use
- Women diagnosed with conditions or undergoing treatments, like chemotherapy, which might affect fertility
- Individuals using donor eggs
What are the prerequisites for Vitrification (Oocyte/Embryo)?
- For oocyte vitrification, hormonal stimulation and egg retrieval processes are necessary
- Consent forms and discussions about the potential risks and benefits
- A thorough assessment of the quality and maturity of oocytes or embryos is done before vitrification
How does Vitrification (Oocyte/Embryo) work?
The process involves:
1
Dehydration
The oocytes or embryos are first dehydrated to remove water content using high concentrations of cryoprotectants
2
Rapid Freezing
They are then quickly plunged into liquid nitrogen at a temperature of -196°C, ensuring an instant transition to a glass-like state without ice crystal formation
3
Storage
The vitrified oocytes or embryos are safely stored in specialized storage devices containing liquid nitrogen (cryo tanks) until they’re needed
Post-Vitrification (Oocyte/Embryo) Procedure
Once verified:
1
The oocytes or embryos remain preserved indefinitely in their current state
2
When required, they undergo a rapid warming process, which reverses the vitrification, making them ready for use in fertility treatments
Frequently Asked Questions
Is vitrification better than traditional freezing methods?
Yes, vitrification usually results in much higher survival rates upon thawing compared to older, slow-freezing methods due to the avoidance of ice crystal formation.
How long can vitrified oocytes or embryos be stored?
Technically, they can be stored indefinitely without a decrease in quality. However, storage duration might be subject to legal or clinic-specific guidelines.
Are there any risks associated with vitrification?
Vitrification and warming are amongst the safest infertility procedures. As with any procedure, there’s potential for risks, but they are minimal. It’s essential to discuss any concerns with your fertility specialist.