Reproductive Immunology - Hegde Fertility - IVF | ICU | ICSI | OI/TI

Reproductive Immunology

Reproductive Immunology

Understanding the Immune System’s Role in Fertility and Pregnancy

Reproductive Immunology is a specialized field that explores how the immune system influences fertility, conception, and the maintenance of a healthy pregnancy. A delicate balance exists between the immune system’s protective functions and its ability to tolerate a genetically unique fetus. When this balance is disrupted, it can contribute to infertility, recurrent miscarriages, and other pregnancy complications.

Why Reproductive Immunology Matters

Many couples struggling with infertility or pregnancy loss may have underlying immunological causes that conventional treatments often overlook. In such cases, targeted immunological testing and therapies can dramatically improve outcomes.

Conditions Linked to Reproductive Immunology

  • Recurrent Pregnancy Loss (RPL): Immune factors such as elevated natural killer (NK) cell activity or autoantibodies can contribute to repeated miscarriages.
  • Unexplained Infertility: In some cases, the immune system may mistakenly attack a fertilized embryo or interfere with implantation.
  • Implantation Failure in IVF: Abnormal immune responses may prevent successful embryo implantation during assisted reproductive procedures.
  • Autoimmune Disorders: Conditions like lupus, antiphospholipid syndrome, and thyroid autoimmunity can interfere with reproductive success.

Key Immune Factors Evaluated

  • Natural Killer (NK) Cells
  • Endometrial immune profiling
  • Cytokine Profiles
  • Antiphospholipid Antibodies
  • HLA Compatibility
  • Antinuclear Antibodies (ANA)
  • Thyroid Autoantibodies

Advanced Immunological Treatments

Our clinic offers personalized treatments designed to modulate immune responses and improve reproductive outcomes. These may include:

  • Immunotherapy (e.g., IVIG, LIT, intralipid infusions)
  • Corticosteroids to reduce inflammation
  • Low-dose aspirin or heparin for clot prevention
  • Lifestyle and dietary modifications
  • Targeted supplements to support immune balance

Who Should Consider Reproductive Immunology Evaluation?

  • Couples with unexplained infertility
  • Women with two or more miscarriages
  • Patients with failed IVF cycles
  • Individuals diagnosed with autoimmune disorders
  • Women experiencing pregnancy complications, such as preeclampsia or intrauterine growth restriction (IUGR)

Compassionate Care, Cutting-Edge Science

At Hegde Fertility, we combine advanced reproductive immunology with individualized care to uncover hidden causes of infertility and pregnancy loss. Our goal is to help you achieve and sustain a healthy pregnancy through science-backed, compassionate solutions.

 

Take the next step in your fertility journey, schedule a consultation with our reproductive immunology experts today.

Request An Appointment