Endometrial PRP (Platelet Rich Plasma) - IVF | ICU | ICSI | OI/TI

Endometrial PRP (Platelet Rich Plasma)

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What is Endometrial PRP?

Endometrial PRP (Platelet-Rich Plasma) therapy is a medical procedure that uses a patient’s blood, which is injected or applied to the endometrium, the lining of the uterus. This procedure is sometimes considered a potential treatment for certain reproductive and gynecological conditions, including infertility and recurrent miscarriages. Additionally, PRP promotes better embryo implantation by increasing the level of growth factors, increasing progesterone receptors and promoting the proliferation of endometrial cells.

Who Can Opt For Endometrial PRP?

Endometrial PRP is recommended for patients who have:

  • Thin endometrium
  • Multiple failed embryo transfers
  • Uterine adhesions
  • Miscarriages
  • Chronic endometritis

What are the prerequisites for Endometrial PRP?

The main prerequisite for Endometrial PRP is a patient’s blood sample, which will be processed to extract the PRP. The patient needs to be in good health, and any contraindications should be discussed with the treating physician.

How does Endometrial PRP work?

How does Endometrial PRP work?

1

Drawing a blood sample

Drawing a sample of the patient’s blood

2

Centrifuged the blood sample

The blood sample is centrifuged for approximately 15 minutes to separate its components

3

Collect Platelet Rich Plasma and load into a syringe with a catheter

The Platelet Rich Plasma, which is now rich in platelets and devoid of other cellular components, is collected and loaded into a syringe with a catheter

4

Endometrial preparation

This loaded sample is then used during the embryo transfer cycle as part of the endometrial preparation

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Two ways of Endometrial PRP

  • Injecting it directly into the cavity
  • Sub-endometrial installation, where the sample is injected beneath the superficial endometrium under hysteroscopy guidance

Post-Endometrial PRP procedure

After the procedure, the enhanced endometrium is more receptive to embryo transfer, increasing the chances of successful implantation. As with any medical procedure, patients should monitor for any unusual symptoms and follow any post-procedure instructions or recommendations provided by their healthcare provider.