Female FertilityFertility Tests

What to Expect During an ERA Test: Preparation, Procedure, and Results

Synopsis:

The ERA (Endometrial Receptivity Array) test is an important diagnostic tool that helps optimize the timing of embryo transfer during IVF. By identifying the optimal “implantation window,” the ERA test can significantly increase the chances of a successful pregnancy. This blog will walk you through what to expect during the ERA test, from preparation to understanding the results.

Preparing for the ERA Test

Before the ERA test, your fertility specialist will likely recommend a mock cycle, which mimics the hormone levels of an actual IVF cycle. You may need to take hormonal medications such as progesterone to prepare your endometrium for the biopsy.

The ERA Test Procedure

The ERA test involves a biopsy of the endometrial lining, which is usually performed about five to seven days after ovulation or progesterone administration. The procedure is relatively quick and is done in your fertility clinic. While it can cause some discomfort similar to menstrual cramps, it is generally well-tolerated.

What Happens After the Biopsy?

The biopsy sample is sent to a specialized laboratory where the expression of 238 genes related to endometrial receptivity is analyzed. This analysis helps identify the exact time when your endometrium is most receptive to an embryo.

Understanding Your ERA Test Results

The ERA test results typically fall into one of three categories:

  • Receptive: Indicates that the timing of the biopsy was perfect, and the endometrium is ready for embryo transfer.
  • Non-Receptive: Suggests that the biopsy was taken either too early or too late in the implantation window. Your doctor will adjust the timing of your embryo transfer accordingly.
  • Pre-Receptive or Post-Receptive: Indicates that the optimal implantation window is either slightly earlier or later than the biopsy timing.

A Word from Hegde Fertility

The ERA test is a valuable tool for anyone undergoing IVF, particularly those who have experienced failed implantation in previous cycles. By tailoring the timing of embryo transfer to your unique biology, the ERA test can improve your chances of a successful pregnancy.

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