Tracing the Genetic Causes of Male Infertility

Tracing the Genetic Causes of Male Infertility

Generally a man’s role in achieving pregnancy seems to be very simple but, very few people know that 60 % of the pregnancy failures are caused due to male infertility. The most common symptoms of male infertility include:

  • Hair growth changes
  • Change in sexual desire
  • Pain and lump formation in testicles
  • Erection and ejaculation problem

Genetic Causes of Male Infertility

Genetic factors are one of the common causes of male infertility.

Y Chromosome Problem

Normal men carry both X and Y chromosome and normal women carries 2 X chromosomes. According to the research 20% of the male infertility is caused due to the loss of Y chromosome. According to the researchers, the first mutation on Y chromosome can prevent sperm production thus, can lead to male infertility.

Genetic analysis is necessary before planning a pregnancy. If the male partners want to use assisted reproductive technology, there is a high risk of transferring a genetic defect to their male offspring. Usually researchers look for Y chromosome as a cause of infertility. In addition to Y chromosome, autosomes, non-sex determining chromosomes or sex-neutral chromosomes are also checked for clues related to infertility.

Other causes of Male Infertility

Apart from genetic defects there are many other factors that can lead to male infertility. The physical flaws like obstruction in the tubes through which the sperms needs to travel or varicose veins in the scrotum can also cause infertility in men.

In few cases men lack vas deferens, the tube that is responsible for transporting sperms from testicles. In such cases surgery is done but, when surgery cannot solve such problems, treatments like ICSI (intra-cytoplasmic sperm injection) can be used. During ICSI, a single sperm is taken and inserted into woman’s egg for fertilization.

Sub-fertility is the common term used for cases related to defects in chromosomes. Sub fertility is generally considered for decreased fertility or inability to get pregnant. Sub-fertility can be treated with different treatments like IVF, IUI and ICSI. ICSI is commonly used in case of genetic defect.

Apart from normal infertility treatments, Cloning and sex selection are the common techniques used to prevent the transmission of a genetic defect to the offspring. Cloning process involves extraction of genetic code to create a replica of the donor. Sex selection involves the separation of the X and Y chromosome. Separation and number of cells in the embryo helps in determining whether the cell is a male or female.

Infertility in men can be cured with proper treatment and a healthy lifestyle. If you are experiencing any of the symptoms related to infertility, you must consult the infertility specialists available in different branches of Hegde fertility center:

IVF center in Kondapur is one of the best IVF centers in Hyderabad for IVF treatments. Infertility treatment cost  is very reasonable and the treatment can be done at an affordable rates.

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