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One of the benefits of opting for In Vitro Fertilisation (IVF) is that patients may be tested for potential genetic problems before attempting a cycle. Preimplantation Genetic Testing for Aneuploidies (PGT-A or PGS) and Preimplantation Genetic Testing for Monosomies (PGT-M or PGD) are extra stages of the procedure that patients are able to opt for if they are worried that there may be factors that might prevent them from conceiving without complications. This is especially useful for determining whether a couple is liable to pass a genetically inherited abnormality on to their child. It may also be recommended for older patients, for those who have suffered multiple unexplained pregnancy losses or for those who have been through multiple failed rounds of IVF.

PGT is an additional service which can offer peace of mind to those wanting to rule out problems.

There is a slight difference between PGT-A and PGT-M:

PGS or PGT-A screens for any chromosomal abnormalities that may be present, while PGD or PGT-M looks out for something specific.

If one or both of the parents are at risk of a particular chromosomal abnormality, PGD or PGT-M may be the right choice. Couples, or even single patients, who have a high risk of chromosomal abnormalities will be identified during their initial consultations, where their medical history will be discussed at length.

PGT-A or PGS on the other hand is a more suitable option for patients who have suffered unexplained miscarriages, or who are over 40 and want to start their cycle of IVF with all the facts at hand. Opting to carry out PGS will mean that the patients are aware of any issues that may prevent them from conceiving without genetic complications, and may even be offered the opportunity to avert them. Only healthy embryos are selected for transfer into the uterus. Opting for IVF with preimplantation genetic screening or preimplantation genetic diagnosis, will give you the best possible chance of falling pregnant on a sound genetic basis.