IMSI (Intracytoplasmic Morphologically Selected Sperm Injection)

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What is IMSI?

IMSI treatment in Hegde Fertility is a brief name for Intracytoplasmic Morphologically Selected Sperm Injection. The sperms are assessed using a highly magnifying microscope in the procedure of IMSI in Hegde Fertility.

In conventional ICSI in Hegde Fertility,  sperms are magnified 200 times, allowing the embryologist to study the motility (motility) and the head of the sperm. Thereby, leading to the selection of the most competent sperm to inject into the egg.

On the other hand, with the help of IMSI embryologists can see the sperm head in a lot more detail, and also some particular features in the head of the sperm which can be associated with incorrect DNA packing. This incorrect packaging makes the sperm more prone to oxidative damage. In turn, it leads to decreased pregnancy chances and increased rates of miscarriages.


The IMSI method is developed by Mr. Benjamin Bartoov, who used a microscope to select sperms with a good shape and size which indicated better genetic quality. The pregnancy rate in patients successfully increased from 30% to 60%.


The new microscope helps magnifies the image of the sperm 7,200 times. Its magnification capacity is 16 times higher than the ICSI (intracytoplasmic sperm injection) machine.

IMSI Treatment advice

  • Severe male infertility
  • Low sperm count
  • Low motility of the sperms
  • Abnormality in shape of the sperms
  • Increased levels of DNA fragmentation
  • History of recurrent miscarriages in the partner
  • Failure of multiple ICSI procedures
  • Poor quality of embryos
  • Unexplained infertility

It may not be suitable for patients with very low numbers of sperms. as it is a selection process, there should be enough sperms to start with.

The Procedure from reputed Fertility Centre

The patient is requested to produce a fresh sample of semen. It is then washed. The sperms are examined under the microscope. The sperms are magnified 7200 time their normal size. With this microscope, many sperm defects can be identified which was not possible with the conventional ICSI machine microscope. Now the Our Infertility Specialists will examine the head of the sperm in a lot more detail, and the sperm with a better morphology(shape and size) and motility can be selected. Hence, the best quality sperm can be selected with the help of this new technique.

After selecting the sperm, the standard procedure of ICSI treatment in Hegde Fertility is followed and the sperm head is injected into the egg cytoplasm for fertilization to occur.

Because of superior sperms, IMSI leads to better egg fertilization rates which cause better quality embryos to form, better rate of Blastocyst formation and therefore better chances of maintaining the pregnancy. Want to know more about IMSI??  Contact us for knowing the details on IMSI treatment and infertility treatment cost.