Pre-Implantation Genetic Screening

Pre-implantation Genetic Screening is used to test embryos for any genetic problem or chromosome abnormality. The process is mainly used to select only chromosomally normal embryos or those free from any genetic disorders for transfer during an IVF cycle in different IVF centres, increasing their chances of having a healthy baby.

Around 70% of embryos created either through natural conception or IVF do not survive the first 3 months of pregnancy due to the aforementioned reasons.

Recommended cases

You may need to undergo Pre-implantation Genetic Screening if:

  • Both partners are carriers of single gene mutations
  • Partner has a chromosome rearrangement that can produce genetically abnormal eggs or sperm
  • Pregnancy has been affected by a chromosomal abnormality
  • Advanced maternal age
  • Recurrent miscarriage
  • Recurrent implantation [IVF] failure

PGS Procedure

The procedure involves undergoing a conventional IVF procedure. When embryos are in developing stage, a few cells are removed from each embryo and tested in one of the two ways:

Advanced Embryo Selection (Array Cgh):

The procedure involves screening all 24 chromosomes in an embryo to facilitate the process of selection and transfer of chromosomally normal embryos.


If both of you are a carrier of a single gene disorder, then Karyomapping is performed. The procedure helps identifies the embryos that are not affected by the disorder, thus prevents the condition to transfer to the next generation.

Benefits of PGS

  • The procedure can be used to test over 100 genetic conditions
  • PGS is carried out before implantation thus allowing the couple to decide on whether they want pregnancy
  • Couples can have biological children

Risks of PGS

The following are a few risks associated with PGS:

  • Although PGS helps reduce the chances of giving a birth to child with genetic disorder, it cannot eliminate the risk. In few cases, further testing is required during pregnancy to eliminate the genetic disorder completely
  • Pre-implantation genetic screening does not substitute the prenatal testing.

Hope you got required information about the Preimplantation genetic screening. If you want to know more, consult our Infertility specialist right away. You can find ivf cost, iui cost, icsi treatment cost by contacting us at 040-4260 7310.  Book an Appointment now!